单中心回顾性研究纳入218例静脉窦型ASD合并PAPVC患者。手术方式：Warden术式（上腔静脉-右心房吻合+补片引流）142例，经典补片修补76例。住院死亡率0.5%，上腔静脉梗阻发生率3.2%（Warden术式组1.4% vs 经典组6.6%，p=0.04）。术后10年免除再手术率96%。推荐…
多中心研究纳入年龄>40岁的ASD患者648例。晚期诊断的成人ASD患者中，术前NYHA III-IV级的占42%。封堵/手术后5年心功能改善率85%，但术前合并房颤者房颤持续率高达60%。年龄>60岁手术者主要并发症发生率显著升高（OR 2.3, p=0.01）。提示成人ASD应尽早干预，即使无症…
综述了ASD合并PAH的诊疗进展。研究纳入386例ASD-PAH患者，肺血管阻力（PVR）<5 Wood单位组手术/封堵后5年生存率98%，PVR 5-8 Wood单位组经靶向治疗后手术的5年生存率89%，PVR>8 Wood单位组仅62%。推荐PVR>5 Wood单位者先接受3-6个月靶向药物治疗…
一项纳入1420例ASD患者的对比研究（封堵组820例，外科组600例）显示，10年随访期间介入封堵组和外科组在全因死亡（1.2% vs 0.8%，p=0.45）、主要心脑血管事件（2.1% vs 1.7%，p=0.38）方面无显著差异。介入封堵组住院时间显著缩短（2.3天 vs 5.7天，p<0.…
Contemporary early mortality for complete TOF repair in infants is approximately 1-3% in major centers.…
Adults with repaired TOF demonstrate reduced exercise capacity and lower quality of life scores, with RV dysfunction being the strongest predictor.…
Pulmonary valve replacement after TOF repair results in significant reduction of RV volumes and improvement in exercise capacity.…
Late morbidity after TOF repair is dominated by pulmonary regurgitation, right ventricular dilation, arrhythmias, and reoperation.…
Tetralogy of Fallot is the most common cyanotic congenital heart disease, with repair outcomes showing 30-year survival exceeding 85%.…
Children undergoing ASO for TGA have lower scores on neurodevelopmental assessments compared to population norms, highlighting the need for long-term …